What is PEP?
PEP stands for post-exposure prophylaxis and is a prescribed medication that aids in the prevention of HIV, when taken within 72 hours (3 days) after possible exposure. PEP is prescribed in pill form and must be taken every day for at least 28 days to be effective.
Who can be prescribed PEP?
PEP can be prescribed to anyone who does not have HIV or does know their HIV status, and in the last 72 hours:
- May have been exposed to HIV during sex.
- Shared needles or other equipment to inject drugs.
If any of the above describe you or you think you’ve been exposed to HIV, talk to a Matthew 25 provider or an emergency room doctor about starting PEP immediately.
Is PEP safe?
Overall PEP is safe, but it may cause side effects in some people. These side effects are typically mild and may include: diarrhea, nausea, tiredness, and headaches.
Before taking PEP, be sure to consult a Matthew 25 provider about any possible side effects caused by PEP. If you are actively taking PEP, contact your provider if you have any side effects that bother you or do not go away.
Is PEP effective?
According to the NIH, PEP is roughly 80% effective at preventing HIV when it is taken within 72 hours of exposure.
- PEP’s effectiveness heavily depends on medication adherence across the 28-day period and no additional exposures to HIV.
- PEP is most effective when started as soon as possible after a potential HIV exposure and must be started within 72 hours (3 days). If you are approaching the 72-hour window and our clinic is closed, seek care immediately at an emergency room or urgent care to discuss starting PEP.
What next?
After taking PEP, our providers may discuss potential HIV prevention options with you like PrEP and safer sex practices. Our goal is to serve you and provide you the support you need, to feel in control of your sexual health regardless of your circumstances.